After three consecutive losses - one of which occurred against the Browns on a missed 41-yard field goal with six seconds left - I'm buying low on the 49ers.

Each team is off their bye. The timing works out much better for San Francisco. I'm expecting Deebo Samuel and offensive left tackle Trent Williams to return to the 49ers' lineup following the extra time off. That will make Brock Purdy reach peak efficiency again.

Jacksonville entered its bye winning and covering five in a row. That momentum could get stalled.

The Jaguars have come up with 18 takeaways, an average of 2.2 per game. If the 49ers play a clean game, they should win being the superior team.

Trevor Lawrence remains inconsistent. He's going to encounter a strong 49ers defense that will be bolstered by the return to health of underrated linebacker Dre Greenlaw and the addition of defensive line stud Chase Young from the Commanders. Nick Bosa is way overdue for a big game, too. It could come here.