Through the first six quarters of their season, the Giants were outscored, 60-0. They regrouped to pull out a 31-28 victory against the Cardinals - the worst team in the NFL. Scoring 31 points in the second half to pull out that road victory in the Arizona desert has to take a lot out of the Giants both physically and mentally. They lost their superstar running back, Saquan Barkley, to an ankle injury, too, in that win.

The NFL did the Giants no favor by making them the road team for a Thursday game against the 49ers, who are one of the three-best teams in the NFL.

I don't see how the Giants can stay within single-digits of the 49ers given the short-week circumstances and the quality of the defenses.

Brock Purdy is 10-0 in games he has started and finished for the 49ers. The Giants surrendered four TD's and nearly 400 yards to the pop-gun offense of the Cardinals. Now they go from Joshua Dobbs and his cast of grunts to Purdy, Christian McCaffrey, Deebo Samuel, George Kittle and Brandon Aiyuk backed by a real coaching staff.

Daniel Jones needs weapons to be successful. He won't have his main one, Barkley. His wide receivers don't frighten anyone least of all the 49ers.

This one isn't going to be close.