No coach is better at specific defensive game-planning than Bill Belichick. The Rams found that out the hard way when they lost 13-3 to the Patriots two seasons ago in the Super Bowl. The Rams averaged 32.9 points during the regular season that year. 
Jared Goff is a quarterback who doesn't keep Belichick awake at night. Belichick's schemes completely stymied Goff, who enters this matchup averaging two turnovers per game during his last five games. 
New England has shown plenty of defense the past two weeks holding Arizona to 17 points and shutting out the Chargers. The Patriots held Kyler Murray and Justin Herbert to a combined 4.4 yards per pass attempt, one touchdown pass with four interceptions and five sacks. 
The Rams rank in the top-five in all of the major defensive categories, giving up the second-fewest yards. The Patriots have failed to break 21 points in six of their last nine games. 
The Patriots rely heavily on their ground game. They have played ultra-conservative this season because of lack of firepower. Cam Newton never was a highly accurate passer and his throwing has regressed. The Rams rank third in run defense. They also give up the fewest 20-plus yards completion so don't look for many big plays from New England.