The Giants are in must-win mode at 0-3. They should have beaten the Eagles last week. The Giants allowed the second-fewest points in the NFL last season and their defense remains top-rate.

Offense has been a major problem for the Giants. But things should click better now that Odell Beckham Jr. is healthy. The timing is good here for the Giants because the Buccaneers have a cluster injury problem on defense with their top defenders injured. Likely out for sure are linebackers Lavonte David and Kwon Alexander. The Buccaneers also could be missing their two best defensive linemen, Gerald McCoy and Chris Baker, along with cornerbacks Brent Grimes and Vernon Hargreaves. Promising pass rusher Noah Spence also is hurt with a separated shoulder.

Eli Manning has never lost to Tampa Bay going 5-0. The Buccaneers have failed to cover eight of the last nine times when laying more than two points.

The Giants won 11 games last season on their way to making the playoffs. The Buccaneers last made the postseason in 2007. The timing is ripe here for the Giants to get back on track against an inconsistent Bucs offense and extremely banged-up defense.