The Colts are home, have the better skill position players and I like their quarterback better.

The Browns have lost their last 14 road games. Rookie quarterback DeShone Kizer has been sacked 10 times and picked off four times in six quarters. He'll be without his top receiver, injured Corey Coleman.

The Colts acquired second-year quarterback Jacoby Brissett from the Patriots on Sept. 2. Brissett had only seven practices before starting this past Sunday against the Cardinals. He nearly led the Colts to an upset win against the Cardinals with Indy losing in overtime. Brissett has excellent mobility and a big arm. He helped lead the Patriots to an easy win against the Texans, a much stronger defensive team than the Browns, last season.

The Colts have more skill position weapons for Brissett than the Browns do for Kizer, including elite wideout T.Y. Hilton. The Browns will be without Myles Garrett and possibly star linebacker Jamie Collins, who is in the league's concussiohn protocol.