This is a case of going over the total with a top 10 scoring team in the Giants against a buy-low underachieving 49ers offense that has talent and is facing the league's worst pass defense.

In today's NFL, with the rules heavily skewed in favor of offense, a total in this range is low.

Not only did the Giants enter this week ranked 32nd in pass defense giving up 316.3 yards per game through the air, but they had surrendered the 26th most overall yards. Colin Kaepernick has the receiving weapons to take advantage with Torrey Smith and a still good Anquan Boldin.

The 49ers catch the Giants missing a number of defensive players, including linebacker Devon Kennard and pass rusher Robert Ayers.

San Francisco gave a strong defensive effort at home last week against Green Bay. But the 49ers are way down defensively due to retirements and free agency losses. They have been at their worst on the road giving up 47 points to the Cardinals and 43 to the Steelers. On the season, the 49ers give up the fourth-highest passer rating and are tied for second-worst with a 9.2 yard per pass attempt against. The 49ers have given up seven touchdown passes in their last three games with only one interception.

The 49ers also could be without one their better defensive players, linebacker Ahmad Brooks. His sister died this week so he may not play.

Eli Manning and Odell Beckham Jr. can light up this low caliber of defense.