Buffalo learned Saturday its roster will be light four players, including standout CB Josh Norman, because of COVID-19 restrictions. The other three are starters and oft-used backups. Three of the four are DBs, so QB Kyler Murray could torch a patchwork secondary.
This Arizona run game should carve up the Bills defense, and Arizona is a solid 11th in pass defense.

The Bills aren't going to travel well in this spot and you can expect a big bounce back game for Arizona here at home. We're backing the Cardinals here at home minus the short number on Sunday evening.