Louisville at Mississippi 8:00 ET
Cardinals (+) over Rebels- There are plenty of storylines to follow from head coaches to player accomplishments on both sides of the ball. Mississippi's head coach Lane Kiffin enters his second season at Mississippi and he had the top offense in the SEC last season. Meanwhile Louisville's defense was ranked fourth in the ACC last year and have seven defensive starters returning. The Cardinals don't have no longer has the likes of Lamar Jackson as they have turned into a defensive club that was stingy giving up points but they do have the return of quarterback Malik Cunningham. Mississippi had the SEC's worst defense with a low of 16 sacks but, the Rebels led the SEC in rushing with and that's why the total is at 75.5. Take LOUISVILLE!