Arizona at San Diego 9:00 ET
Chargers over Cardinals- Both the Cardinals and Chargers lost their preseason opener each scoring just 10 points respectively. Arizona has now failed to 'cover' in any of their past four outings including the regular season, playoffs and their 30-10 loss to Oakland last week while San Diego was pounded 27-10 at Tennessee. With questions surrounding Bruce Arinas' health Arizona will try and stay healthy as injuries have kept many of their key performers off the field. This one means so much more to the Chargers who have to establish a positive atmosphere. Take SAN DIEGO!