Simply put this game means more to the Bills than the Giants. Yes off a disappointing season, Eli Manning and the Giants have plenty to prove, but not until the week after Labor Day.
Buffalo has new weapon Sammy Watkins plus a healthy C.J. Spiller and Fred Jackson. The Bills have made it clear they want to prove they are ready to take the next step and they are the one team that will be in some statement mode. David Wilson NYG RB is out. Look for the Giants to spend more time finding out who will be part of their running game to be too worried about the scoreboard.

We are not as convinced as some may be about the motivational effect of Jim Kelly's presence but it is a factor that should not be ignored. The Bills great is facing a horrible battle with cancer and current players have spoken of his inspiration.

Tom Coughlin, the Giants head man has even specifically said playing times will be determined by position battles and not any concern for the scoreboard. The Bills want to change the culture and bring some optimism. The Giants will be judged by the regular season and not by whether or not a team that has key cogs from two recent Super Bowl titles looks good in exhibition football.

The winning pick: Buffalo -3

Tonight's best picks from Joe Duffy's Picks The first winning pick of the football season is up from Joe Duffy! A Wise Guy play for Sunday Night Hall-of-Fame Game total has been posted between the Giants and Bills. We are 45-29 with all football Wise Guy plays. As always, we are very specific about what we know and reveal all inside.

It is the perfect time to jump on board in MLB. In 27 MLB seasons as a pro handicapper and many more before that as a bettor, we have had some clunkers of a portfolio. But they are exponentially outnumbered by our winning streaks. Off our worst day of the season in MLB history emphatically says payback will be devastating for the sportsboooks while we resume our NFL winnings later in the night. It is all at