The set-up: After taking two of the first three games of this Cubs/White Sox annual Crosstown Classic, the defending champs are now 10-2 since the All Star break and sit 53-47 on the season, a half-game better than the Brewers in the NL Central. With next week's trade deadline rapidly approaching, the Cubs' South Side neighbors are heading in the opposite direction. Wednesday's 8-3 loss means the White Sox have lost 14 in their last 16 games, giving them the AL's worst record at 39-59. The White Sox are in "full-blown" rebuilding mode!

The pitching matchup: Jon Lester (7-6 & 3.95 ERA) will start for the Cubs, while the White Sox counter with Mike Pelfrey (3-7 & 4.46 ERA). Lester hopes to continue the strong effort the Cubs have gotten from their starters since the All-Star break, as Cubs starters are 9-0 with eight quality starts and have posted a 2.50 ERA. Lester had that nightmare start right before the break (recorded just two outs and allowed 10 runs, although only four were earned, against the Pirates) but has returned from the break to post back-to-back wins (1.80 ERA). Lester is 6-6 with a 4.43 ERA in 14 starts vs. the White Sox in his career (teams are 8-6). I guess one could point to Pelfrey's 2-0 career mark vs. the Cubs with a 1.66 ERA in three outings (teams are 3-0) but that's really a small sample size. Pelfrey last won back on June 17 vs. Toronto, with the team going 1-4 in his five starts since. On the season, the White Sox are 6-10 in his starts.

The pick: The Cubs bats have come alive, as they have averaged 6.0 RPG since the break but while it is a small sample size, Pelfrey has pitched very well against the Cubs. As for Lester, he had a great second-half in 2016 and has begun 2017 the same way (1.80 ERA in B2B wins since the break). Make the Under a 10* play.