The Detroit Tigers are sitting at the top of the AL Central with a record of 9-1, but their offense has cooled off in recent games. They won a pitcher's duel at home in Game 1 yesterday, and they've only scored five runs over their last three games. Runs won't come easy this afternoon against Chicago's ace.

Here are my keys to the game:

1. Pitching - Chris Sale will get the nod for the White Sox, and he was impressive in his season debut. Sale (1-0, 1.50 ERA) allowed just one run on five hits, while fanning eight over six innings in a home win over the Twins. He's pitched very well against the Tigers in his career, going 3-2 with a 1.71 ERA in his last seven starts versus Detroit. The Tigers counter with Anibal Sanchez, who was roughed up by the Pirates in Pittsburgh in his most recent start.

2. Batter vs. Pitcher - Miguel Cabrera is widely considered to be the best hitter in the major leagues, but he hasn't had a lot of success versus Sale. He's 6-for-30 with 11 strikeouts lifetime versus the southpaw.

3. X-Factor - Sanchez was 0-2 with a 4.97 ERA in two starts versus the White Sox last year.

Selection: This is a play on the Chicago White Sox.(10*)