The Miami Dolphins have lost five of seven following a 3-0 start and I think they'll lose big at Indianapolis Sunday afternoon. Sure, the Dolphins are coming off their bye and QB Ryan Tannehill is finally back in the lineup after missing five games, but can he make that big of a difference? "I'm not quite 100 percent," Tannehill said. "But I'm confident I've made all the throws I will need over the course of a game. I don't feel like any aspect of my game has been taken away."

The meanwhile Colts are red hot coming off four straight victories and QB Andrew Luck threw for 297 yards and three touchdowns against Tennessee last week to be named the AFC Offensive Player of the Week. He has now thrown for at least three touchdowns in seven consecutive games and figures to do plenty of damage again here.

Colts are 15-5-1 ATS in their last 21 games in November. Dolphins are 1-5-1 ATS in their last 7 games in November.

8* play on Indianapolis Colts.