This is an 8* MOTIVATIONAL MISMATCH on the Buffalo Bills.

This games means a lot more to the Bills than it does to the visiting Lions who will simply go through the motions and consider themselves victors if they can leave Buffalo without any injuries. Bills' starting QB EJ Manuel and his first unit are expected to see more than usual playing time for the fourth week of the preseason as the coaching staff is less than impressed so far with the chemistry: "Yes, absolutely, I'm looking to play those guys," head coach Marrone said this week. "I think, obviously, we're much further ahead on (the defensive side) of the ball than we are (on offense)." We can expect the first string offense to see extended time today: "If we want to be a great offense, we have to be able to do it against their starters, not their bench," RB C.J. Spiller echoed. "I wouldn't say discouraged. We're disappointed. If we want to be a great offense, we have to be able to do it against their starters, not their bench." We'll see a lot of Dan Orlovsky and Kellen Moore today under center for the visitors as the Lions try to figure out their No. 1 backup. Week 4 is always tricky, but this is a great spot to exploit I feel, Buffalo needs something positive to come into the regular season after such a dismal start, I look for the home side to find a way to cover the spread at the end of the night; play on the BILLS.

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