We really like the favorite in this matchup. The number looks a bit off when you consider that the Cowboys almost blew a big lead against Clemson. As impressive as their first round win was, it's important to remember that the Tigers leading scorer was injured. This team was blown out by Gonzaga in the first round last year, and Purdue should prove to be a far tougher test than a shorthanded ACC team.

This is a 5* play on PUR.