Jimmy Garoppolo is a mediocre quarterback. But he's savvy enough to know how to distribute the ball to his weapons - and he just gained a monster weapon in Christian McCaffrey.

The Rams' defense is far from dominant, surrendering 22 or more points in four of their six games.

Look for the Rams' offense to pick up following their bye. Sean McVay should have some new wrinkles and a healthier offensive line with center Brian Allen returning.

Matthew Stafford and Cooper Kupp will hurt a 49ers defense that has been dealing with multiple injuries to their secondary along with linebacker Dre Greenlaw joining Arik Armstead on the sidelines.