This is far more of a mismatch than this point spread indicates. Louisville has defeated Syracuse the past three times by an average of 30 points, including out-scoring the Orange, 71-3, during the last two meetings.

Louisville owns a monster edge at QB with Malik Cunningham, the top rushing QB in the ACC. Cunningham is protected by a very underrated offensive line.

Syracuse is forced to be one-dimensional on the ground with Sean Tucker because its QB, Garret Shrader, is terrible. Shrader is very inaccurate and he's not helped by a weak group of receivers. Tucker is excellent, but the Cardinals will be stacking the line against him.

The Orange haven't been able to turn the corner under Dino Babers with just 11 victories during the past three years.