There are very few teams the Angels should be favored against when starting Patrick Sandoval - and the Indians aren't one of those teams. 
Cleveland has defeated the Angels eight straight times, outscoring them by nearly three runs a game during this win streak. 

The Indians own a winning road record. The Angels have a sub .500 home mark. 

Southpaw Sam Hentges is set to make his second career start for Cleveland. He tossed 4 2/3 scoreless innings with six strikeouts in his first start five days ago against the Cubs. Hentges has 14 strikeouts in 13 2/3 innings this year. The Angels are 2-9 in their past 11 games versus a lefty starter, including 2-7 this season. They are batting .225 against southpaws. 

The Angels have scored three runs or fewer in 10 of their past 14 games. 

Sandoval has a 6.14 ERA and 1.50 WHIP pitching in relief. This will be his first start of the season. He's expected to be on around a 60-65 pitch count setting up a bullpen game for the Angels, who have the worst team ERA in the majors at 5.32.