LSU had its signature victory upsetting Florida, 37-34, as a monster underdog last week. The Tigers were very fortunate to win that game since they were outgained by nearly 200 yards and gave up 8.9 yards per play while having just 4.9 yards per play. 
The Tigers are in a huge letdown spot and have nothing to play for since they have a self-imposed bowl ban. 
The Tigers will put up plenty of points, but I don't see them keeping up with Mississippi. The Rebels are averaging 39.8 points and rank third in the nation in total yards. LSU allows 33.4 points and is 127th in the country in total defense. 
The Rebels will be the far fresher team having last played on Nov. 28. They have had plenty of time to study and prepare for this matchup and unlike LSU they are not in letdown spot.