I'm not buying Iowa State as a road favorite against TCU. The Horned Frogs have defeated the Cyclones four of the last five times they've hosted them. Iowa State is 0-5-1 ATS the past six times it has laid points. 
TCU should be improved on both sides of the ball. The Horned Frogs are extremely anxious to begin their season after an early postponement. 
Iowa State is 0-1. The Cyclones were upset by Louisiana-Lafayette unable to handle the Ragin Cajuns' big plays. TCU is explosive, too. 
Brock Purdy did not have a good game for Iowa State in that loss. Purdy certainly is worthy of respect, but so is TCU's safety tandem of Ar'Darius Washington and Trevon Moehrig. They are considered by some to be among the best safeties in college football.