The Browns are not well coached. But they do have weapons and can be trusted to put up points when playing bad defenses. You won't find too many NFL defenses as bad as Arizona's. The Cardinals give up the most yards per game and also rank last in pass defense. They have surrendered 21 or more points in every game. 
Baker Mayfield should do well versus this low caliber of defense. So should Nick Chubb, who leads the NFL in rushing. 
Arizona should contribute its share of points. The Cardinals have three good running backs. The Browns rank 26th in run defense. 
As a side note, there is bad blood between Mayfield and Cardinals head man Kliff Kingsbury stemming from when Mayfield played for Kingsbury at Texas Tech before he transferred to Oklahoma. So both teams will be looking to run up a score with no letdowns.