Miles Mikolas loves to pitch at Busch Stadium. Mikolas was 8-4 with a 2.17 ERA pitching at Busch Stadium in his first season with the Cardinals last year. He's followed that up with a winning home mark and a 2.55 ERA at Busch this season. The Angels have managed just three runs during the first two games of this series.

St. Louis is 12-4 in Mikolas' last 16 home starts.

Tyler Skaggs has been less effective on the road for the Angels with a 5.27 away ERA. The Cardinals have scored four or more runs in eight of their last 10 games.