At 0-4, Colorado is desperate to get its first Pac-12 victory. I see that happening here against a USC team minus injured big man Benny Boatwright and who plays much worse on the road. The Trojans have dropped three of their last four games. They are 1-8 ATS in their last nine games.

Colorado had to play its first three conference games on the road and then drew fourth-ranked UCLA at home.

The Buffaloes are 7-1 against USC since joining the Pac-12. They have covered five of the past times versus the Trojans.