Southern Illinois should stay competitive and cover this spread against Oklahoma State. They are a scrappy team and have performed well when they step up in class. Southern Illinois is 9-2 ATS in their last 11 games against an opponent in the Big 12 conference. The Cowboys have struggled at home to cover games as they have gone 0-5 ATS in their last five home games. Southern Illinois has won their last two games against them so they should get up in this spot and should be a close competitive game.

Best bet: take the points with Southern Illinois.