Louisville's stats in the last three games have taken a nosedive and they are on the road again where they are 1-6 against the spread in that situation and come into this game off of some ugly losses. Louisville has always struggled in Chestnut Hill, and the home team has won each of the last seven games played. The Cardinals are also giving up over 469 total yards to opponents in the ACC and are more turnover prone on the road this season. Boston College also faced some losses on the road but now they are a big underdog at home where they are 3-0 ATS. BC should dictate the pace and slow down the game with long drives headed by Castellanos as their underrated defense will keep this game close. Louisville struggles to stop the run so they will have to throw on this Eagles team who can frustrate them with their pass defense too and slow them down as well. BC also has the rest advantage while this is a short week for the Cardinals. This game is going to be a closely fought game so getting a touchdown is good value with the home team. Louisville is 0-5 ATS as a road favorite and they are 0-7 ATS as a favorite of 3.5 to 10 points on the road.

Best bet: take the points with Boston College.