The Titans are coming off a huge win over the Chiefs last week so a letdown could be expected. The Titans have a chance to put even more distance between themselves and the Colts in the division so I expect them to come out hard right from the opening kickoff. Derek Henry has been almost unstoppable and Tannehill does just enough in the passing game to make them dangerous. Indianapolis lost week three to the Titans but have been playing better after an 0-3 start to the season. The Colts have won three of the last four with Cason Wentz playing a lot better than he did to open the season. The Colts have not shown the ability to stop Derrick Henry and that could be the case again today. Tennessee is 4-1 ATS in their last 5 division games and 5-1 ATS in their last 6 games overall. Indianapolis is 4-1 ATS in their last 5 games against a team with a winning record and 3-7 ATS in their last 10 division games.

Play on Tennessee.