San Francisco will come out on top with the win in this one and even with their injuries, will still find a way to dominate. The running game hasn't missed a beat, which should allow them to control the game, while they expect to only be without Samuel from the wide receiver room and missing their TE Kittles. When looking at the Rams, they lack the downfield talent to compete with the 49ers, and with Stafford likely under duress for much of the game he'll be pressured and Rams missing 2 key WR's they will find it out to score in the redzone. The 49ers should roll here on Sunday and get the win and ATS cover for us.