Overall I see more upside in San Francisco in this matchup. The 49ers are 17th in the NFL, averaging 5.7 yards per play, and the Bears are dead-last picking up just 4.4 yards per play. The 49ers are eight in the NFL, allowing 4.9 yards per play, and the Bears are 14th giving up 5.5 yards per play. Although Jimmy G has struggled this year, he has been much better than Justin Fields. I expect San Francisco to win and cover on the road.