Yusei Kikuchi will get handed the ball for Seattle, making his first start of the season. Kikuchi went 2-4 last season with a 5.17 ERA while striking out 9 batters per nine innings. He has not faced the Giants yet in his career. Set to make his first start of the year is right-hander Johnny Cueto. He went 2-3 with a 5.4 ERA last season. Dating back to last year, the Mariners are 4-0 in their last 4 games facing a right-handed starter. They are 5-1 in their last 6 as a favorite.