The Diamondbacks beat Tyler Anderson in his opening start, allowing seven runs in just over two innings. But I think he will bounce back here against a weaker San Diego team that he's had a lot of success against. Anderson has just a 2.00 ERA in his three career starts against the Padres, winning two of them. The Padres are going with Joey Lucchesi. Lucchesi made his first career start on Friday and wasn't very good. He is not an MLB-caliber starter and was a surprise addition to the roster this year. His highest level prior to this season was a stint at Double-A. And now he's facing a tough Colorado lineup that should bat him around. Colorado had the highest batting average in the Majors against left-handed pitching last year and they are off to a solid start this season. The Rockies are 10-3 in the last 13 games in this series and they are 5-2 in their last seven in San Diego.