Seattle at San Francisco 4:25 ET
49ers (-) over Seahawks- The Seattle Seahawks come off one of the most impressive victories of the season with their total annihilation of the Saints (Megabucks Winner) last Monday Night. There are a number of solid handicapping reasons as to why we should be on San Francisco. To start with is the revenge factor in how the Seahawks dominated the 49ers earlier in the season at Seattle and probably more important is the drop-off in the level of play to be suffered by the 'Hawks after their huge win. No question of how Seattle had the best of the last two meetings out-scoring the Niners 71-16. If San Francisco has any shot (at least physiologically) to represent the West again they need a win here. Take SAN FRANCISCO!