Chip's NFL Power Play Winner
(NFL) San Francisco vs. Carolina,
Point Spread: 6.50 | -108.00 Carolina (Home)
Result: Loss
San Francisco at Carolina 4:05 ET
Panthers (+) over 49ers- The 49ers hold the NFL's top defense a month into the season, limiting opponents to 11.5 points per game. Yet it could be a tough turnaround for the 49ers (2-2), who topped the Los Angeles Rams 24-9 on Monday night and then must make a cross-country trip. For now, the Panthers (1-3) appear to have more problems. In quarterback ratings, Mayfield is 30th, while San Francisco's Jimmy Garoppolo is 14th. The Panthers have won six of the last eight matchups with San Francisco, including three in a row at home in regular-season play. They do it again. Take CAROLINA!