Philadelphia at Arizona 4:25 ET
Cardinals (+) over Eagles- The Philadelphia Eagles (4-0) also started 4-0 and made it to 7-0 before going all the way to Super Bowl XXXIX that season. The Cardinals (2-2) are 0-2 at home and have alternated wins and losses entering Week 5. Eagles quarterback Jalen Hurts, an early MVP candidate with 1,120 passing yards and four touchdown passes plus 205 yards and four more scores on the ground. Cardinals counterpart Kyler Murray leads the NFL through four games in pass completions (113) and attempts (173). In his only previous start against Philadelphia, Murray completed 27 of 36 passes for 406 yards, three touchdowns and one interception in a 33-26 win at home on Dec. 20, 2020. Philadelphia's last road win against Arizona was in 2001. Take ARIZONA!