Major
(NFL) Miami vs. Houston,
Point Spread: 3.00 | 109.00 Miami (Away)
Result: Loss
There are many overlapping systems, including if the game loses the hook. I know it is +3 +120 or so some places. However, the most statistically significant of them is going with preseason road underdogs of 3.5 or more after allowing three points or less in the first half versus an opponent off double-digit win is 66-35. Still such angles as going with road teams after allowing 14 points or less last game against opponent off double-digit win is 43-21.

In short, there are many angles that verify our own experience that favorites off big wins as preseason faves.