The Colts were unable to stop Ben Roethlisberger in a 51-34 loss at Pittsburgh last week. The Steelers QB threw for 522 yards and six TDs, but perhaps it was more a matter of good execution by the Steelers offense, than poor defense from the Colts. Given that Big Ben followed up with another six TD performance against the Ravens last night, it would seem to indicate that the Steelers offense is firing onall cylinders. The same can't be said about the Giants, and their defense should struggle to stop Andrew Luck.

Here are my keys to the game:

1. Giants Defense - The NFL's leading passer will be matched against a Giants secondary that ranks 25th in the NFL allowing 262 passing yards per game. Tony Romo lit them up in their last game, throwing for 279 yards and three TDs in a 31-21 Cowboys win.

2. Injuries - The Giants wimiss their top receiver (Cruz), starting RB (Jennings) and DT Cullen Jenkins.

3. X-Factor - The Giants have failed to cover four of their last five games versus teams with a winning record.

Selection: This is a play on the Indianapolis Colts ML (8*)