The set-up: "The Prodigal Son" returns to his former stomping grounds, looking to dominate on the road. For a number of different reasons, I absolutely believe that Justin Verlander and the defending champs on the run-line (-1.5) is the correct move. The Tigers send Francisco Liriano to the hill.

The pitchers: Verlander is so far 14-9 with a 2.73 ERA. He's been trading good starts with bad ones of late (for his incredibly high standards anyways), but he has to be feeling confident here, coming in sporting the still elite 11-2, 2.26 ERA on the road this season.

Liriano is so far 4-9 with a 4.90 ERA. He has been a disappointment for a second straight year and he can't be feeling too confident at all here, as note that he's a terrible 2-3 with a 5.55 ERA at home.

The pick: Take it for what you will as well, but the Astros are 7-2 in their last nine night American League road games in which they are a favorite in the -200 to -300 range. Lay the 1.5 runs on Houston in this one.