The set-up: Kick Cousins makes his Vikings debut against the 49ers and QB Jimmy Garappolo. The 49ers blew up their team after ten games last year and they never looked back with Garappolo under center. That said, I think he'll be in for a rude awakening at what will undoubtedly be a rowdy atmosphere at the US Bank Stadium.

The teams: Garoppolo was 5-0 as a starter for San Francisco last year. It was an unbelievable run, but regression seems imminent in my opinion.

The Vikings possessed the best defensive unit in the league last year, one which was even better in front of the home town crowd.

The pick: This is an "early," release, so I plan on updating my analysis as we get closer to game time. However, over the time of this release and when this one kicks off, I do indeed expect this line to climb. Normally at this time of year the defensive units are many steps ahead of the offensive side and that's exactly what I'm expecting in this one. Combined with the competent Cousins and a Vikings team looking to take out its frustrations after the loss in the NFC Championship Game last year, this one has "blowout" written all over it in my opinion. Lay the points, play on the Vikes.