The set-up: This series features a couple of of competitive match-ups on the mound and this is one of them. Runs would appear to be at a premium tonight. The visitors hand the ball to Brett Anderson, while the home side goes with Gerritt Cole.

The pitchers: Anderson is so far 3-3 with a 3.47 ERA. He most recently went seven shutout innings against the Rangers on Tuesday, giving up a single hit and striking out six. Anderson has now worked back to back shutout seven frame performances and he's won three of his last four starts overall, posting a tiny 0.68 ERA over 26.2 frames of work this month.

Cole is so far 11-5 with a 2.73 ERA. He most recently gave up three runs while striking out seven over five innings in a no-decision to the Mariners on Monday. Note that Cole is a sharp 5-2 with a 2.67 ERA at home.

The pick: Take it for what you will, but Houston has now seen the total go "under" the number in eight of its last 12 night home games in which it's a favorite in the -125 to -200 range. This number is a little high considering how well these starters are performing at the moment, play the "under."