The set-up: This series features a couple of competitive match-ups on the mound, and this is one of them. For a number of different reasons though, I think this one favors Miles Mikolas and the hard-hitting home side. The visitors turn to Wade Miley.

The pitchers: Miley is so far 2-1 with a 2.23 ERA. It's hard to say anything negative about Miley, I simply feel that he's in the wrong place at the wrong time here (note that St. Louis is 7-2 in it last nine night time home games as a favorite in the -125 to -150 range.)

Mikolas is so far 12-3 with a 2.85 ERA. His peripherals suggest that his numbers are sustainable. That said he'll be looking to get back on track here after allowing four runs over seven innings in a no-decision to the Nationals on Monday. Previous to this sub-par effort Mikolas hadn't allowed more than three earned runs since mid June though.

The pick: There's absolutely no reason not to think that Mikolas can't bounce back here, as note that he's already 5-2 with a 2.29 ERA at home this season. Miley's been good, but I like Mikolas to out-duel his counterpart today and for the Cards to take advantage. Lay the price.