The set-up: I think that the massive talent-gap on the mound absolutely makes Zack Greinke and the hard-hitting visiting the side the correct call in this inter-league match-up. The Rangers send the venerable Bartolo Colon to the hill tonight.

The pitchers: Greinke is so far 12-7 with a 2.89 ERA. He most recently gave up one run off three hits and four walks while striking out four over seven innings against the Phillies on Tuesday. Over his last five starts spanning 35.2 frames of work Greinke has a tiny 1.26 ERA and overall he sports an elite 152:23 K/BB.

Colon is so far 6-10 with a 5.18 ERA. He most recently gave up four runs off eight hits while striking out just one over seven innings in a fortunate victory over the Mariners on Tuesday. With the victory Colon became the all time Latin American wins leader. Can anyone say "letdown spot?" Note that he's a terrible 3-4 with a 5.65 ERA at home this year.

The pick: Take it for what you will as well, but Arizona is 8-2 in its last ten road inter-league games in which its a favorite in the -125 to -200 range. No upsets here as I look for Greinke to come in focused and to easily out duel his inconsistent counterpart. Lay the price, play on Arizona.