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(NBA) San Antonio vs. Miami,
Point Spread: -3.50 | -113.00 San Antonio (Away)
Result: Win
The set-up: The Spurs have opened 3-0, despite missing all-everything forward Kawhi Leonard, who remains out while dealing with right quadriceps tendinopathy. The Spurs have also made do without long-time PG Tony Parker (left quadriceps tendon surgery). San Antonio travels to South Beach Wednesday night to face the Miami Heat, who have opened 2-1. Miami center Hassan Whiteside is expected to miss his third straight game with a bone bruise on his left knee. Ironically, Whiteside went for 26 & 22 in Miami's season-opener at Orlando but the Heat lost. Without Whiteside, the team has won home games over the Pacers and Hawks.

San Antonio: LaMarcus Aldridge has stepped up with Leonard out, averaging 24.3 & 9.3. He is also helping out on the defensive end and provided the highlight of Monday's 101-97 win over the Raptors with a chase-down block of Toronto point guard Kyle Lowry as the Spurs held their third consecutive opponent under 100 points to start the season. Dejounte Murray surprisingly beat out Patty Mills in training camp for the right to replace Tony Parker as the team's starting PG and he's been up to the challenge, averaging 13.3-9.7-4.7. Danny Green 14.3) and Rudy Gay (12.3) also averaging in double digits.

Miami: Along with Whiteside, PG Dragic (quad bruise) and SG Waiters (ankle) are also hurting for Miami. Dragic plans to be available for Wednesday's game and if Waiters is unable to go, the Heat have plenty of other options at the shooting guard spot. Josh Richardson had a team-high 21 points in Miami's win over Atlanta and is averaging 14.3 PPG, while Wayne Ellington came off the bench and buried 6-of-8 from three-point range against the Hawks, after going 2-of-10 from beyond the arc in the first two games.

The pick: Both teams are dealing with injury issues but the absence of Whiteside is a bigger concern in this game. Jordan Mickey started the last two games in place of Whiteside and averaged five points and six rebounds in 14.5 minutes. That worked vs. the Pacers and Hawks but will not vs. the Spurs, who are holding opponents to just 91.0 PPG, despite playing without Leonard (arguably, the league's best defensive player). San Antonio enters this contest having won nine straight in the series, going back to Game 3 of the 2014 NBA Finals. Make the Spurs an 8* play.