The Pittsburgh Steelers will head out on the road to take on the San Diego Chargers on Monday Night Football, and both these teams have their fair share of injuries. Mike Vick will get another chance to lead Pittsburgh to a win, after his team blew it last Thursday at home against Baltimore. Vick played well enough to win, and if he can do it again Monday, I like the Steelers chances of covering here in San Diego.

Here are my keys to the game:

1. Chargers Defense - San Diego barely escaped with a 30-27 win at home over Cleveland last week, and career backup Josh McCown lit them up for 356 yards and a pair of TDs. They have allowed opponents to average 27.5 points per game during a 2-2 start.

2. Previous History - The Steelers have covered the spread in four straight road games, while the Chargers have only managed to cover once in their last seven home games.

3. X-Factor - The Chargers were without three starters on the offensive line in last week's game versus Cleveland, and all three missed practice on Wednesday.

Selection: This is a play on the Pittsburgh Steelers (10*)