The 12th-seeded Liberty Flames managed to defeat No. 5 seed Mississippi State despite closing as a 7-point dog in the first round. I think their Big Dance adventure will come to an end here against the fourth-seeded Virginia Tech.

I'm not sure if even Liberty believes it can win this game. "The stuff they run offensively is nightmares to prepare for," Flames coach Ritchie McKay said of the Hokies. "I was back at the hotel … and started watching film, and I finally gave up."

The Hokies biggest asset is their defense though. They have held opponents to 61.8 ppg on the season and limited Saint Louis to 36.5% shooting from the field and 4-for-23 from three-point range in a 66-52 victory in their first round matchup. "It's a known precedent that if you play Virginia Tech, you're going to make shots and have your best shooting night," Tech point guard Justin Robinson cracked after the game.

VT is 6-1 ATS in its last seven neutral site games while the Flames are 3-9 ATS in their last 12 neutral site games.

8* play on Virginia Tech Hokies.