Taking ARIZONA here. We cashed with the Cardinals are our Top 10* last week, and we nearly made them another 10* here this week. This team fell apart last year. Now with a new regime, that will not happen. The defense is a good unit. The offense now has a legit NFL QB who has a Hall of Fame talented WR to throw the ball to. I know the Lions are everyone's sexy pick. But come on! This team is totally undisciplined and can blow a gasket at anytime. Lions are 3-11 SU on the road as favorites. Finally, a dome team playing on grass in the desert? Whatever edge you think the Lions have, you are mistaken. They will be out-coached, out-hustled and out-played here as the Cardinals open up new HC Arians first home game with a nice win. 5* Best Bet ARIZONA CARDINALS