San Francisco has been knocked out of playoff contention and is playing for pride in the final two weeks of the season. The 49ers are banged up with their top two running backs on the shelf while Guerendo missed last week’s game and has been limited in practice this week. Detroit rebounded from their loss to Buffalo as they took care of business against the Bears. The Lions have plenty to play for with a week 18 matchup with the Vikings looming that could determine not only the top spot in the NFC North but also home field advantage in the NFC playoffs. Detroit takes care of business here as they shut down the 49ers to maintain momentum heading into that showdown.